The STEM CELL TIMES
22 мая 2019, среда, 4:59
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04.10.2017 Считаете ли Вы, что трансплантация стволовых клеток взрослого организма может вызвать онкологическое заболевание?


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Growth factors

     Growth factors are the main regulators of growth, development and cell balance maintenance processes. Cellular consistency of rapidly renewing tissues (blood, epithelium), for example, depends on activation, proliferation and differentiation of tissue-specific stem cells and is regulated with different growth factors. As an example of growth factors, EGF (epidermal growth factor),FGF (fibroblast growth factor), PDGF (platelet derived growth factor), VEGF (vessel endothelial growth factor), IGF (insulin-like growth factor) and many others can be mentioned.

     Despite the fact that the name of these factors reflects the cellular lines this doesn't mean that their effect is restricted to this cell line. The most factors are universal. They affect many cell types, stimulating their proliferation and differentiation, or inhibit their activity. But almost every process in the body is controlled by their specific combination. Growth factors mediate the impact of one cell on others.

     Dermal fibroblasts that synthesize a number of GF can be an example of the cell's interaction with the other cell types of the skin. Basic FGF activates the vessel growth (angiogenesis), TGF-beta (transforming growth factor) defines chemotropism (the directed cells migration according to the chemical agent gradient concentration) of fibroblasts and, besides, the synthesize of intercellular compounds; KGF (keratinocyte growth factor) accelerates wounds regeneration; EGF (epithelial growth factor) activates proliferation and migration of keratinocytes (epidermal cells). Besides bFGF expression stimulates other cells of skin, it activates fibroblasts themselves. So growth factors regulate basic processes of regeneration and maintain the balance of all tissue compounds.

     All these notions of the growth factors biological role in processes of all skin elements made a ground to the research work of the Center of cells technologies of youth Beauty PLAZA to create the Youth activator. The Youth activator is a unique complex of biotechnological components, that is based on growth factors application that activates intrinsic fibroblasts. It is applicated locally in the areas that requires drastic rejuvenation. After its injections the native collagen increases, that normally occurs only in the young skin. The incremental synthesis of native collagen provides the biological youth of tissues and has long-lasting effect of face, neck, décolleté, arms and body rejuvenation.

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Development center cell research aimed at establishing and standardizing the collection of stem cells, multipotent mesenchymal stromal cells (ITC) and fibroblasts were the basis for the National Bank of stem cells and fibroblasts.

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Srivastava, Rakesh K.; Shankar, Sharmila (издатели)
Stem cells - the body builders
                Cells of the human body are divided into ordinary and stem cells ordinary adult cells can not transform                 in another cell type , and can not induce embryogenesis . In humans,                 ninety allocated different types of cells , so the cells are those molecules                 which consists of an organism, stem cells and the organism is reduced . for                 storage of stem cells used Cryobank                 , Prior to entering the cell which is cooled in a freezer program steps                 one degree per minute. Thereafter, in special capsules , frozen to minus                 seventy degrees , the cells are placed into containers , numbered barcode                 in a special pot with liquid nitrogen , and our bank retains biological resources over 5500 patients.                 For storage of the concentrated stem cells and mononuclear cells derived from                 umbilical cord blood after birth, used Gemabank , there they are in special                 plastic plates and in order to highlight the desired cells are required for more                 manipulation. Longevity and beauty of a person   problem in the 21st century , which pay attention to not only women but also men and  successful resolution of this matter modern methods , such as cell technology allow a person to turn the modern ideas about resolving this problems . Learn more information about stem cell therapy you can in the appropriate section of our portal.