Collagen is the most abundant protein in a human body, it makes up to 20-30% of total protein. It provides tissues for special mechanical strength and, besides, affects
the growth, migration, differentiation, secretion and synthetic cells' activity. It also assures the correct tissue elements distribution and supplies its structure. Due to collagen fibers skin is so resilient in its young state. Collagen fibrils are always renewed, the process of their synthesis and disintegration is highly organized and is accomplished by fibroblasts. But during aging this balance breaks, the synthesis of new fibers slows down, with appearance of an increasing number of cross-links. This process leads to collagen's almost complete in-extensibility with impaired processes of its utilization. .
Collagen fibrils are strong and flexible but not elastic. Elastin is another protein of connective tissue. These two proteins, collagen and elastin, make the derma framework. Elastin is less abundant in comparing with collagen and its main function is providing skin for resilience (the ability to obtain initial state after strain). Dermal elastin is also synthesized by fibroblasts and during aging according to cells senescence its synthesis slows down, that leads to skin age-related changes. .
Collagen and elastin are indeed proteins of youth. They provide skin
for elasticity, freshness and beauty but also are the main components of other organs and preserve their health and youth. Collagen and elastin determine tendon, bone and chondro tissues functional state. Osteoarthritis, osteoporosis, ostichondrosis — all these diseases are linked to the structure of these proteins one way or another. .
Thereby the main trend of our body youth and health retainment is maintainance of collagen and elastin balance of synthesis and disintegration. In this case it is highly important not only to lead a healthy life but «омолаживать» also to rejuvenate these protein main fabrics. Nowadays it has become possible to maintain the population of young cells in the body, for example fibroblasts, to increase the resistance of the body to aggressive environmental factors..